2-Hydroxyphenacyl bromide

2-Hydroxyphenacyl bromide - Names and Identifiers

Name	2-Bromo-2'-hydroxyacetophenone
Synonyms	BRN 0637210 2-HYDROXYPHENACYL BROMIDE 2-Hydroxyphenacyl bromide 2-Bromo-2'-hydroxyacetophenone 2-bromo-1-(2-hydroxyphenyl)-ethanon 2-BROMO-1-(2-HYDROXYPHENYL)ETHANONE 2-Bromo-1-(2-hydroxyphenyl)ethanone Ethanone, 2-bromo-1-(2-hydroxyphenyl)- 2-broMo-1-(2-hydroxyphenyl)ethan-1-one 4-08-00-00329 (Beilstein Handbook Reference) Acetophenone, 2-bromo-2'-hydroxy- (6CI,7CI,8CI) 2-Bromo-2'-hydroxyacetophenone, 2-Bromo-1-(2-hydroxyphenyl)ethan-1-one, 2-(Bromoacetyl)phenol
CAS	2491-36-3
InChI	InChI=1/C8H7BrO2/c9-5-8(11)6-3-1-2-4-7(6)10/h1-4,10H,5H2

2-Hydroxyphenacyl bromide - Physico-chemical Properties

Molecular Formula	C8H7BrO2
Molar Mass	215.04
Density	1.622±0.06 g/cm3(Predicted)
Melting Point	44-48°C(lit.)
Boling Point	152-158 °C(Press: 18 Torr)
Flash Point	>230°F
Solubility	Chloroform, Methanol
Vapor Presure	0.00373mmHg at 25°C
Appearance	grayish white powder
Color	Yellow
pKa	7.63±0.30(Predicted)
Storage Condition	Keep in dark place,Inert atmosphere,2-8°C
Sensitive	Lachrymatory
Refractive Index	1.608
MDL	MFCD01727570

2-Hydroxyphenacyl bromide - Risk and Safety

Hazard Symbols	C - Corrosive
Risk Codes	R22 - Harmful if swallowed R34 - Causes burns
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
UN IDs	UN 3263 8/PG 2
WGK Germany	3
RTECS	KM5556400
HS Code	29147000
Hazard Note	Corrosive/Lachrymatory/Keep Cold
Hazard Class	8
Packing Group	II

2-Hydroxyphenacyl bromide - Introduction

2-Bromo-2 '-hydroxyacetophenone is a chemical substance that has the following properties:

1. Appearance: 2-Bromo-2 '-hydroxyacetophenone is a colorless to slightly yellow crystalline solid.
2. Solubility: It is soluble in organic solvents such as ethanol, acetone and dimethyl sulfoxide, and has low solubility in water.
3. Melting Point: the melting point of 2-Bromo-2 '-hydroxyacetophenone is about 115-119 ℃.
4. Chemical properties: it is an active compound, easily oxidized by oxidizing agents in the air, and can also react with reducing agents.

2-Bromo-2 '-hydroxyacetophenone has several uses in the laboratory and industry:
1. Drug synthesis: It is used as an intermediate in the synthesis of other organic compounds.
2. Chemical research: It can be used as a catalyst or reagent for organic synthesis reactions.
3. Polymer chemistry: It can be used as an initiator in polymerization reactions.

A common method for preparing 2-Bromo-2 '-hydroxyacetophenone is through the hydroxylation reaction of bromoacetophenone. The specific synthesis method needs to be carried out in the laboratory or factory.

Regarding safety information, 2-Bromo-2 '-hydroxyacetophenone is an organic compound with potential hazards and risks. Appropriate safety measures are required during handling and use, including wearing protective glasses, gloves and laboratory clothing, ensuring a well-ventilated work environment, and avoiding contact with skin, inhalation or swallowing. In case of contact or inhalation, clean or move to fresh air. Store properly to prevent fire and accidents. Before use, it is recommended to understand its safe operation guidelines in detail and follow relevant regulations. To ensure safe use, it is best to operate in a suitable laboratory environment guided by a professional.

Last Update：2024-04-09 21:32:39